Neuroprotective Effects of Açaí (Euterpe oleracea Mart.) against Rotenone In Vitro Exposure
Identifieur interne : 000269 ( Main/Exploration ); précédent : 000268; suivant : 000270Neuroprotective Effects of Açaí (Euterpe oleracea Mart.) against Rotenone In Vitro Exposure
Auteurs : Alencar Kolinski Machado [Brésil] ; Ana Cristina Andreazza [Canada] ; Tatiane Morgana Da Silva [Brésil] ; Aline Augusti Boligon [Brésil] ; Vanusa Do Nascimento [Brésil] ; Gustavo Scola [Canada] ; Angela Duong [Canada] ; Francine Carla Cadoná [Brésil] ; Euler Esteves Ribeiro [Brésil] ; Ivana Beatrice Mânica Da Cruz [Brésil]Source :
- Oxidative Medicine and Cellular Longevity [ 1942-0900 ] ; 2016.
Abstract
Neuropsychiatric diseases, such as bipolar disorder (BD) and schizophrenia (SCZ), have a very complex pathophysiology. Several current studies describe an association between psychiatric illness and mitochondrial dysfunction and consequent cellular modifications, including lipid, protein, and DNA damage, caused by cellular oxidative stress.
Url:
DOI: 10.1155/2016/8940850
PubMed: 27781077
PubMed Central: 5066013
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neuroprotective Effects of Açaí (<italic>Euterpe oleracea</italic> Mart.) against Rotenone<italic> In Vitro</italic> Exposure</title><author><name sortKey="Machado, Alencar Kolinski" sort="Machado, Alencar Kolinski" uniqKey="Machado A" first="Alencar Kolinski" last="Machado">Alencar Kolinski Machado</name><affiliation wicri:level="2"><nlm:aff id="I1">Postgraduate Program of Pharmacology, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Postgraduate Program of Pharmacology, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="I2">Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation></author><author><name sortKey="Andreazza, Ana Cristina" sort="Andreazza, Ana Cristina" uniqKey="Andreazza A" first="Ana Cristina" last="Andreazza">Ana Cristina Andreazza</name><affiliation wicri:level="4"><nlm:aff id="I3">Department of Psychiatry, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychiatry, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Centre for Addiction and Mental Health, Toronto, ON, 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wicri:level="2"><nlm:aff id="I1">Postgraduate Program of Pharmacology, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Postgraduate Program of Pharmacology, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="I2">Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation></author><author><name sortKey="Andreazza, Ana Cristina" sort="Andreazza, Ana Cristina" uniqKey="Andreazza A" first="Ana Cristina" last="Andreazza">Ana Cristina Andreazza</name><affiliation wicri:level="4"><nlm:aff id="I3">Department of Psychiatry, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychiatry, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Centre for Addiction and Mental Health, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Centre for Addiction and Mental Health, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Da Silva, Tatiane Morgana" sort="Da Silva, Tatiane Morgana" uniqKey="Da Silva T" first="Tatiane Morgana" last="Da Silva">Tatiane Morgana Da Silva</name><affiliation wicri:level="2"><nlm:aff id="I5">Federal University of Pelotas, Pelotas, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Federal University of Pelotas, Pelotas, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation></author><author><name sortKey="Boligon, Aline Augusti" sort="Boligon, Aline Augusti" uniqKey="Boligon A" first="Aline Augusti" last="Boligon">Aline Augusti Boligon</name><affiliation wicri:level="2"><nlm:aff id="I6">Phytochemical Research Laboratory, Department of Industrial Pharmacy, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Phytochemical Research Laboratory, Department of Industrial Pharmacy, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation></author><author><name sortKey="Do Nascimento, Vanusa" sort="Do Nascimento, Vanusa" uniqKey="Do Nascimento V" first="Vanusa" last="Do Nascimento">Vanusa Do Nascimento</name><affiliation wicri:level="2"><nlm:aff id="I2">Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="I7">Third Age Open University, University of Amazonas State, Manaus, AM, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Third Age Open University, University of Amazonas State, Manaus, AM</wicri:regionArea><placeName><region type="state">Amazonas (Brésil)</region></placeName></affiliation></author><author><name sortKey="Scola, Gustavo" sort="Scola, Gustavo" uniqKey="Scola G" first="Gustavo" last="Scola">Gustavo Scola</name><affiliation wicri:level="4"><nlm:aff id="I3">Department of Psychiatry, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychiatry, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Centre for Addiction and Mental Health, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Centre for Addiction and Mental Health, Toronto, ON</wicri:regionArea><wicri:noRegion>ON</wicri:noRegion></affiliation></author><author><name sortKey="Duong, Angela" sort="Duong, Angela" uniqKey="Duong A" first="Angela" last="Duong">Angela Duong</name><affiliation wicri:level="4"><nlm:aff id="I3">Department of Psychiatry, University of Toronto, Toronto, ON, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Psychiatry, University of Toronto, Toronto, ON</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Cadona, Francine Carla" sort="Cadona, Francine Carla" uniqKey="Cadona F" first="Francine Carla" last="Cadoná">Francine Carla Cadoná</name><affiliation wicri:level="2"><nlm:aff id="I2">Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="I8">Postgraduate Program of Biological Sciences, Toxicological Biochemistry, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Postgraduate Program of Biological Sciences, Toxicological Biochemistry, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation></author><author><name sortKey="Ribeiro, Euler Esteves" sort="Ribeiro, Euler Esteves" uniqKey="Ribeiro E" first="Euler Esteves" last="Ribeiro">Euler Esteves Ribeiro</name><affiliation wicri:level="2"><nlm:aff id="I2">Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="I7">Third Age Open University, University of Amazonas State, Manaus, AM, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Third Age Open University, University of Amazonas State, Manaus, AM</wicri:regionArea><placeName><region type="state">Amazonas (Brésil)</region></placeName></affiliation></author><author><name sortKey="Da Cruz, Ivana Beatrice Manica" sort="Da Cruz, Ivana Beatrice Manica" uniqKey="Da Cruz I" first="Ivana Beatrice Mânica" last="Da Cruz">Ivana Beatrice Mânica Da Cruz</name><affiliation wicri:level="2"><nlm:aff id="I1">Postgraduate Program of Pharmacology, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Postgraduate Program of Pharmacology, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="I2">Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Biogenomics Laboratory, Department of Morphology, Health Science Center, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="I8">Postgraduate Program of Biological Sciences, Toxicological Biochemistry, Federal University of Santa Maria, Santa Maria, RS, Brazil</nlm:aff><country xml:lang="fr">Brésil</country><wicri:regionArea>Postgraduate Program of Biological Sciences, Toxicological Biochemistry, Federal University of Santa Maria, Santa Maria, RS</wicri:regionArea><placeName><region type="state">Rio Grande do Sul</region></placeName></affiliation></author></analytic><series><title level="j">Oxidative Medicine and Cellular Longevity</title><idno type="ISSN">1942-0900</idno><idno type="eISSN">1942-0994</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Neuropsychiatric diseases, such as bipolar disorder (BD) and schizophrenia (SCZ), have a very complex pathophysiology. Several current studies describe an association between psychiatric illness and mitochondrial dysfunction and consequent cellular modifications, including lipid, protein, and DNA damage, caused by cellular oxidative stress.<italic> Euterpe oleracea</italic> (açaí) is a powerful antioxidant fruit. Açaí is an Amazonian palm fruit primarily found in the lowlands of the Amazonian rainforest, particularly in the floodplains of the Amazon River. Given this proposed association, this study analyzed the potential<italic> in vitro</italic> neuropharmacological effect of<italic> Euterpe oleracea</italic> (açaí) extract in the modulation of mitochondrial function and oxidative metabolism. SH-SY5Y cells were treated with rotenone to induce mitochondrial complex I dysfunction and before and after we exposed the cells to açaí extract at 5 <italic>μ</italic>g/mL. Treated and untreated cells were then analyzed by spectrophotometric, fluorescent, immunological, and molecular assays. The results showed that açaí extract can potentially increase protein amount and enzyme activity of mitochondrial complex I, mainly through NDUFS7 and NDUFS8 overexpression. Açaí extract was also able to decrease cell reactive oxygen species levels and lipid peroxidation. We thus suggest açaí as a potential candidate for drug development and a possible alternative BD therapy.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Epstein, I" uniqKey="Epstein I">I. Epstein</name></author><author><name sortKey="Szpindel, I" uniqKey="Szpindel I">I. Szpindel</name></author><author><name sortKey="Katzman, M A" uniqKey="Katzman M">M. A. Katzman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Millan, M J" uniqKey="Millan M">M. J. Millan</name></author><author><name sortKey="Goodwin, G M" uniqKey="Goodwin G">G. M. Goodwin</name></author><author><name sortKey="Meyer Lindenberg, A" uniqKey="Meyer Lindenberg A">A. Meyer-Lindenberg</name></author><author><name sortKey="Ove Ogren, S" uniqKey="Ove Ogren S">S. Ove Ogren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alonso, J" uniqKey="Alonso J">J. Alonso</name></author><author><name sortKey="Petukhova, M" uniqKey="Petukhova M">M. Petukhova</name></author><author><name sortKey="Vilagut, G" uniqKey="Vilagut G">G. Vilagut</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grande, I" uniqKey="Grande I">I. Grande</name></author><author><name sortKey="Berk, M" uniqKey="Berk M">M. Berk</name></author><author><name sortKey="Birmaher, B" uniqKey="Birmaher B">B. Birmaher</name></author><author><name sortKey="Vieta, E" uniqKey="Vieta E">E. Vieta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Craddock, N" uniqKey="Craddock N">N. Craddock</name></author><author><name sortKey="Sklar, P" uniqKey="Sklar P">P. Sklar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clay, H B" uniqKey="Clay H">H. B. Clay</name></author><author><name sortKey="Sillivan, S" uniqKey="Sillivan S">S. Sillivan</name></author><author><name sortKey="Konradi, C" uniqKey="Konradi C">C. Konradi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manji, H" uniqKey="Manji H">H. Manji</name></author><author><name sortKey="Kato, T" uniqKey="Kato T">T. Kato</name></author><author><name sortKey="Di Prospero, N A" uniqKey="Di Prospero N">N. A. Di Prospero</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scola, G" uniqKey="Scola G">G. Scola</name></author><author><name sortKey="Kim, H K" uniqKey="Kim H">H. K. Kim</name></author><author><name sortKey="Young, L T" uniqKey="Young L">L. T. Young</name></author><author><name sortKey="Andreazza, A C" uniqKey="Andreazza A">A. C. Andreazza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Andreazza, A C" uniqKey="Andreazza A">A. C. Andreazza</name></author><author><name sortKey="Shoo, L" uniqKey="Shoo L">L. Shoo</name></author><author><name sortKey="Wang, J F" uniqKey="Wang J">J.-F. Wang</name></author><author><name sortKey="Trevor Young, L" uniqKey="Trevor Young L">L. Trevor Young</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berk, M" uniqKey="Berk M">M. Berk</name></author><author><name sortKey="Kapczinski, F" uniqKey="Kapczinski F">F. Kapczinski</name></author><author><name sortKey="Andreazza, A C" uniqKey="Andreazza A">A. C. Andreazza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Akarsu, S" uniqKey="Akarsu S">S. Akarsu</name></author><author><name sortKey="Torun, D" uniqKey="Torun D">D. Torun</name></author><author><name sortKey="Bolu, A" uniqKey="Bolu A">A. Bolu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Beal, M F" uniqKey="Beal M">M. F. Beal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Curran, G" uniqKey="Curran G">G. Curran</name></author><author><name sortKey="Ravindran, A" uniqKey="Ravindran A">A. Ravindran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grunze, H" uniqKey="Grunze H">H. Grunze</name></author><author><name sortKey="Vieta, E" uniqKey="Vieta E">E. Vieta</name></author><author><name sortKey="Goodwin, G M" uniqKey="Goodwin G">G. M. Goodwin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goodwin, G M" uniqKey="Goodwin G">G. M. Goodwin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hou, L" uniqKey="Hou L">L. Hou</name></author><author><name sortKey="Xiong, N" uniqKey="Xiong N">N. Xiong</name></author><author><name sortKey="Liu, L" uniqKey="Liu L">L. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kleiner, J" uniqKey="Kleiner J">J. Kleiner</name></author><author><name sortKey="Altshuler, L" uniqKey="Altshuler L">L. Altshuler</name></author><author><name sortKey="Hendrick, V" uniqKey="Hendrick V">V. Hendrick</name></author><author><name sortKey="Hershman, J M" uniqKey="Hershman J">J. M. Hershman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Markowitz, G S" uniqKey="Markowitz G">G. S. Markowitz</name></author><author><name sortKey="Radhakrishnan, J" uniqKey="Radhakrishnan J">J. Radhakrishnan</name></author><author><name sortKey="Kambham, N" uniqKey="Kambham N">N. Kambham</name></author><author><name sortKey="Valeri, A M" uniqKey="Valeri A">A. M. Valeri</name></author><author><name sortKey="Hines, W H" uniqKey="Hines W">W. H. Hines</name></author><author><name sortKey="D Agati, V D" uniqKey="D Agati V">V. D. D'Agati</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Young, A H" uniqKey="Young A">A. H. Young</name></author><author><name sortKey="Newham, J I" uniqKey="Newham J">J. I. Newham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kang, J" uniqKey="Kang J">J. Kang</name></author><author><name sortKey="Thakali, K M" uniqKey="Thakali K">K. M. Thakali</name></author><author><name sortKey="Xie, C" uniqKey="Xie C">C. Xie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jensen, G S" uniqKey="Jensen G">G. S. Jensen</name></author><author><name sortKey="Wu, X" uniqKey="Wu X">X. Wu</name></author><author><name sortKey="Patterson, K M" uniqKey="Patterson K">K. M. Patterson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poulose, S M" uniqKey="Poulose S">S. M. Poulose</name></author><author><name sortKey="Bielinski, D F" uniqKey="Bielinski D">D. F. Bielinski</name></author><author><name sortKey="Carey, A" uniqKey="Carey A">A. Carey</name></author><author><name sortKey="Schauss, A G" uniqKey="Schauss A">A. G. Schauss</name></author><author><name sortKey="Shukitt Hale, B" uniqKey="Shukitt Hale B">B. Shukitt-Hale</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sun, X" uniqKey="Sun X">X. Sun</name></author><author><name sortKey="Seeberger, J" uniqKey="Seeberger J">J. Seeberger</name></author><author><name sortKey="Alberico, T" uniqKey="Alberico T">T. Alberico</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poulose, S M" uniqKey="Poulose S">S. M. Poulose</name></author><author><name sortKey="Fisher, D R" uniqKey="Fisher D">D. R. Fisher</name></author><author><name sortKey="Bielinski, D F" uniqKey="Bielinski D">D. F. Bielinski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carey, A N" uniqKey="Carey A">A. N. Carey</name></author><author><name sortKey="Miller, M G" uniqKey="Miller M">M. G. Miller</name></author><author><name sortKey="Fisher, D R" uniqKey="Fisher D">D. R. Fisher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poulose, S M" uniqKey="Poulose S">S. M. Poulose</name></author><author><name sortKey="Fisher, D R" uniqKey="Fisher D">D. R. Fisher</name></author><author><name sortKey="Larson, J" uniqKey="Larson J">J. Larson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Odendaal, Y A" uniqKey="Odendaal Y">Y. A. Odendaal</name></author><author><name sortKey="Schauss, A G" uniqKey="Schauss A">A. G. Schauss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Solanki, I" uniqKey="Solanki I">I. Solanki</name></author><author><name sortKey="Parihar, P" uniqKey="Parihar P">P. Parihar</name></author><author><name sortKey="Parihar, M S" uniqKey="Parihar M">M. S. Parihar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schauss, A G" uniqKey="Schauss A">A. G. Schauss</name></author><author><name sortKey="Wu, X" uniqKey="Wu X">X. Wu</name></author><author><name sortKey="Prior, R L" uniqKey="Prior R">R. L. Prior</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schauss, A G" uniqKey="Schauss A">A. G. Schauss</name></author><author><name sortKey="Wu, X" uniqKey="Wu X">X. Wu</name></author><author><name sortKey="Prior, R L" uniqKey="Prior R">R. L. Prior</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garcia Lafuente, A" uniqKey="Garcia Lafuente A">A. García-Lafuente</name></author><author><name sortKey="Guillam N, E" uniqKey="Guillam N E">E. Guillamón</name></author><author><name sortKey="Villares, A" uniqKey="Villares A">A. Villares</name></author><author><name sortKey="Rostagno, M A" uniqKey="Rostagno M">M. A. Rostagno</name></author><author><name sortKey="Martinez, J A" uniqKey="Martinez J">J. A. Martínez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gonzalez Gallego, J" uniqKey="Gonzalez Gallego J">J. González-Gallego</name></author><author><name sortKey="Sanchez Campos, S" uniqKey="Sanchez Campos S">S. Sánchez-Campos</name></author><author><name sortKey="Tu N, M J" uniqKey="Tu N M">M. J. Tuñón</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xie, C" uniqKey="Xie C">C. Xie</name></author><author><name sortKey="Kang, J" uniqKey="Kang J">J. Kang</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nicholas, C" uniqKey="Nicholas C">C. Nicholas</name></author><author><name sortKey="Batra, S" uniqKey="Batra S">S. Batra</name></author><author><name sortKey="Vargo, M A" uniqKey="Vargo M">M. A. Vargo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, L" uniqKey="Zhao L">L. Zhao</name></author><author><name sortKey="Wang, J L" uniqKey="Wang J">J.-L. Wang</name></author><author><name sortKey="Liu, R" uniqKey="Liu R">R. Liu</name></author><author><name sortKey="Li, X X" uniqKey="Li X">X.-X. Li</name></author><author><name sortKey="Li, J F" uniqKey="Li J">J.-F. Li</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Patil, S P" uniqKey="Patil S">S. P. Patil</name></author><author><name sortKey="Jain, P D" uniqKey="Jain P">P. D. Jain</name></author><author><name sortKey="Sancheti, J S" uniqKey="Sancheti J">J. S. Sancheti</name></author><author><name sortKey="Ghumatkar, P J" uniqKey="Ghumatkar P">P. J. Ghumatkar</name></author><author><name sortKey="Tambe, R" uniqKey="Tambe R">R. Tambe</name></author><author><name sortKey="Sathaye, S" uniqKey="Sathaye S">S. Sathaye</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cai, M" uniqKey="Cai M">M. Cai</name></author><author><name sortKey="Ma, Y" uniqKey="Ma Y">Y. Ma</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamagata, K" uniqKey="Yamagata K">K. Yamagata</name></author><author><name sortKey="Kitazawa, T" uniqKey="Kitazawa T">T. Kitazawa</name></author><author><name sortKey="Shinoda, M" uniqKey="Shinoda M">M. Shinoda</name></author><author><name sortKey="Tagawa, C" uniqKey="Tagawa C">C. Tagawa</name></author><author><name sortKey="Chino, M" uniqKey="Chino M">M. Chino</name></author><author><name sortKey="Matsufuji, H" uniqKey="Matsufuji H">H. Matsufuji</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klimaczewski, C V" uniqKey="Klimaczewski C">C. V. Klimaczewski</name></author><author><name sortKey="Saraiva, R D A" uniqKey="Saraiva R">R. D. A. Saraiva</name></author><author><name sortKey="Roos, D H" uniqKey="Roos D">D. H. Roos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abbas, S R" uniqKey="Abbas S">S. R. Abbas</name></author><author><name sortKey="Sabir, S M" uniqKey="Sabir S">S. M. Sabir</name></author><author><name sortKey="Ahmad, S D" uniqKey="Ahmad S">S. D. Ahmad</name></author><author><name sortKey="Boligon, A A" uniqKey="Boligon A">A. A. Boligon</name></author><author><name sortKey="Athayde, M L" uniqKey="Athayde M">M. L. Athayde</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, H K" uniqKey="Kim H">H. K. Kim</name></author><author><name sortKey="Mendonca, K M" uniqKey="Mendonca K">K. M. Mendonça</name></author><author><name sortKey="Howson, P A" uniqKey="Howson P">P. A. Howson</name></author><author><name sortKey="Brotchie, J M" uniqKey="Brotchie J">J. M. Brotchie</name></author><author><name sortKey="Andreazza, A C" uniqKey="Andreazza A">A. C. Andreazza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Andreazza, A C" uniqKey="Andreazza A">A. C. Andreazza</name></author><author><name sortKey="Wang, J F" uniqKey="Wang J">J.-F. Wang</name></author><author><name sortKey="Salmasi, F" uniqKey="Salmasi F">F. Salmasi</name></author><author><name sortKey="Shao, L" uniqKey="Shao L">L. Shao</name></author><author><name sortKey="Young, L T" uniqKey="Young L">L. T. Young</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Costa, F" uniqKey="Costa F">F. Costa</name></author><author><name sortKey="Dornelles, E" uniqKey="Dornelles E">E. Dornelles</name></author><author><name sortKey="Manica Cattani, M F" uniqKey="Manica Cattani M">M. F. Mânica-Cattani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mimaki, M" uniqKey="Mimaki M">M. Mimaki</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Mckenzie, M" uniqKey="Mckenzie M">M. McKenzie</name></author><author><name sortKey="Thorburn, D R" uniqKey="Thorburn D">D. R. Thorburn</name></author><author><name sortKey="Ryan, M T" uniqKey="Ryan M">M. T. Ryan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brazier Hicks, M" uniqKey="Brazier Hicks M">M. Brazier-Hicks</name></author><author><name sortKey="Evans, K M" uniqKey="Evans K">K. M. Evans</name></author><author><name sortKey="Gershater, M C" uniqKey="Gershater M">M. C. Gershater</name></author><author><name sortKey="Puschmann, H" uniqKey="Puschmann H">H. Puschmann</name></author><author><name sortKey="Steel, P G" uniqKey="Steel P">P. G. Steel</name></author><author><name sortKey="Edwards, R" uniqKey="Edwards R">R. Edwards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Law, B N T" uniqKey="Law B">B. N. T. Law</name></author><author><name sortKey="Ling, A P K" uniqKey="Ling A">A. P. K. Ling</name></author><author><name sortKey="Koh, R Y" uniqKey="Koh R">R. Y. Koh</name></author><author><name sortKey="Chye, S M" uniqKey="Chye S">S. M. Chye</name></author><author><name sortKey="Wong, Y P" uniqKey="Wong Y">Y. P. Wong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simirgiotis, M J" uniqKey="Simirgiotis M">M. J. Simirgiotis</name></author><author><name sortKey="Schmeda Hirschmann, G" uniqKey="Schmeda Hirschmann G">G. Schmeda-Hirschmann</name></author><author><name sortKey="B Rquez, J" uniqKey="B Rquez J">J. Bórquez</name></author><author><name sortKey="Kennelly, E J" uniqKey="Kennelly E">E. J. Kennelly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yoo, H" uniqKey="Yoo H">H. Yoo</name></author><author><name sortKey="Ku, S K" uniqKey="Ku S">S.-K. Ku</name></author><author><name sortKey="Lee, T" uniqKey="Lee T">T. Lee</name></author><author><name sortKey="Bae, J S" uniqKey="Bae J">J.-S. Bae</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="An, F" uniqKey="An F">F. An</name></author><author><name sortKey="Yang, G D" uniqKey="Yang G">G. D. Yang</name></author><author><name sortKey="Tian, J M" uniqKey="Tian J">J. M. Tian</name></author><author><name sortKey="Wang, S H" uniqKey="Wang S">S. H. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mathew, S" uniqKey="Mathew S">S. Mathew</name></author><author><name sortKey="Abraham, T E" uniqKey="Abraham T">T. E. Abraham</name></author><author><name sortKey="Zakaria, Z A" uniqKey="Zakaria Z">Z. A. Zakaria</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Popovi, M" uniqKey="Popovi M">M. Popović</name></author><author><name sortKey="Caballero Bleda, M" uniqKey="Caballero Bleda M">M. Caballero-Bleda</name></author><author><name sortKey="Benavente Garcia, O" uniqKey="Benavente Garcia O">O. Benavente-García</name></author><author><name sortKey="Castillo, J" uniqKey="Castillo J">J. Castillo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hollman, P C H" uniqKey="Hollman P">P. C. H. Hollman</name></author><author><name sortKey="Katan, M B" uniqKey="Katan M">M. B. Katan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Praag, H" uniqKey="Van Praag H">H. van Praag</name></author><author><name sortKey="Lucero, M J" uniqKey="Lucero M">M. J. Lucero</name></author><author><name sortKey="Yeo, G W" uniqKey="Yeo G">G. W. Yeo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rangel Ord Ez, L" uniqKey="Rangel Ord Ez L">L. Rangel-Ordóñez</name></author><author><name sortKey="Noldner, M" uniqKey="Noldner M">M. Nöldner</name></author><author><name sortKey="Schubert Zsilavecz, M" uniqKey="Schubert Zsilavecz M">M. Schubert-Zsilavecz</name></author><author><name sortKey="Wurglics, M" uniqKey="Wurglics M">M. Wurglics</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Milbury, P E" uniqKey="Milbury P">P. E. Milbury</name></author><author><name sortKey="Kalt, W" uniqKey="Kalt W">W. Kalt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, D Y S" uniqKey="Wong D">D. Y. S. Wong</name></author><author><name sortKey="Musgrave, I F" uniqKey="Musgrave I">I. F. Musgrave</name></author><author><name sortKey="Harvey, B S" uniqKey="Harvey B">B. S. Harvey</name></author><author><name sortKey="Smid, S D" uniqKey="Smid S">S. D. Smid</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Halliwell, B" uniqKey="Halliwell B">B. Halliwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scola, G" uniqKey="Scola G">G. Scola</name></author><author><name sortKey="Kim, H K" uniqKey="Kim H">H. K. Kim</name></author><author><name sortKey="Young, L T" uniqKey="Young L">L. T. Young</name></author><author><name sortKey="Salvador, M" uniqKey="Salvador M">M. Salvador</name></author><author><name sortKey="Andreazza, A C" uniqKey="Andreazza A">A. C. Andreazza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guerra, J F D C" uniqKey="Guerra J">J. F. D. C. Guerra</name></author><author><name sortKey="Magalhaes, C L D B" uniqKey="Magalhaes C">C. L. D. B. Magalhães</name></author><author><name sortKey="Costa, D C" uniqKey="Costa D">D. C. Costa</name></author><author><name sortKey="Silva, M E" uniqKey="Silva M">M. E. Silva</name></author><author><name sortKey="Pedrosa, M L" uniqKey="Pedrosa M">M. L. Pedrosa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masella, R" uniqKey="Masella R">R. Masella</name></author><author><name sortKey="Di Benedetto, R" uniqKey="Di Benedetto R">R. Di Benedetto</name></author><author><name sortKey="Vari, R" uniqKey="Vari R">R. Varì</name></author><author><name sortKey="Filesi, C" uniqKey="Filesi C">C. Filesi</name></author><author><name sortKey="Giovannini, C" uniqKey="Giovannini C">C. Giovannini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lannuzel, A" uniqKey="Lannuzel A">A. Lannuzel</name></author><author><name sortKey="Hoglinger, G U" uniqKey="Hoglinger G">G. U. Höglinger</name></author><author><name sortKey="Champy, P" uniqKey="Champy P">P. Champy</name></author><author><name sortKey="Michel, P P" uniqKey="Michel P">P. P. Michel</name></author><author><name sortKey="Hirsch, E C" uniqKey="Hirsch E">E. C. Hirsch</name></author><author><name sortKey="Ruberg, M" uniqKey="Ruberg M">M. Ruberg</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Brésil</li><li>Canada</li></country><region><li>Amazonas (Brésil)</li><li>Ontario</li><li>Rio Grande do Sul</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Brésil"><region name="Rio Grande do Sul"><name sortKey="Machado, Alencar Kolinski" sort="Machado, Alencar Kolinski" uniqKey="Machado A" first="Alencar Kolinski" last="Machado">Alencar Kolinski Machado</name></region><name sortKey="Boligon, Aline Augusti" sort="Boligon, Aline Augusti" uniqKey="Boligon A" first="Aline Augusti" last="Boligon">Aline Augusti Boligon</name><name sortKey="Cadona, Francine Carla" sort="Cadona, Francine Carla" uniqKey="Cadona F" first="Francine Carla" last="Cadoná">Francine Carla Cadoná</name><name sortKey="Cadona, Francine Carla" sort="Cadona, Francine Carla" uniqKey="Cadona F" first="Francine Carla" last="Cadoná">Francine Carla Cadoná</name><name sortKey="Da Cruz, Ivana Beatrice Manica" sort="Da Cruz, Ivana Beatrice Manica" uniqKey="Da Cruz I" first="Ivana Beatrice Mânica" last="Da Cruz">Ivana Beatrice Mânica Da Cruz</name><name sortKey="Da Cruz, Ivana Beatrice Manica" sort="Da Cruz, Ivana Beatrice Manica" uniqKey="Da Cruz I" first="Ivana Beatrice Mânica" last="Da Cruz">Ivana Beatrice Mânica Da Cruz</name><name sortKey="Da Cruz, Ivana Beatrice Manica" sort="Da Cruz, Ivana Beatrice Manica" uniqKey="Da Cruz I" first="Ivana Beatrice Mânica" last="Da Cruz">Ivana Beatrice Mânica Da Cruz</name><name sortKey="Da Silva, Tatiane Morgana" sort="Da Silva, Tatiane Morgana" uniqKey="Da Silva T" first="Tatiane Morgana" last="Da Silva">Tatiane Morgana Da Silva</name><name sortKey="Do Nascimento, Vanusa" sort="Do Nascimento, Vanusa" uniqKey="Do Nascimento V" first="Vanusa" last="Do Nascimento">Vanusa Do Nascimento</name><name sortKey="Do Nascimento, Vanusa" sort="Do Nascimento, Vanusa" uniqKey="Do Nascimento V" first="Vanusa" last="Do Nascimento">Vanusa Do Nascimento</name><name sortKey="Machado, Alencar Kolinski" sort="Machado, Alencar Kolinski" uniqKey="Machado A" first="Alencar Kolinski" last="Machado">Alencar Kolinski Machado</name><name sortKey="Ribeiro, Euler Esteves" sort="Ribeiro, Euler Esteves" uniqKey="Ribeiro E" first="Euler Esteves" last="Ribeiro">Euler Esteves Ribeiro</name><name sortKey="Ribeiro, Euler Esteves" sort="Ribeiro, Euler Esteves" uniqKey="Ribeiro E" first="Euler Esteves" last="Ribeiro">Euler Esteves Ribeiro</name></country><country name="Canada"><region name="Ontario"><name sortKey="Andreazza, Ana Cristina" sort="Andreazza, Ana Cristina" uniqKey="Andreazza A" first="Ana Cristina" last="Andreazza">Ana Cristina Andreazza</name></region><name sortKey="Andreazza, Ana Cristina" sort="Andreazza, Ana Cristina" uniqKey="Andreazza A" first="Ana Cristina" last="Andreazza">Ana Cristina Andreazza</name><name sortKey="Duong, Angela" sort="Duong, Angela" uniqKey="Duong A" first="Angela" last="Duong">Angela Duong</name><name sortKey="Scola, Gustavo" sort="Scola, Gustavo" uniqKey="Scola G" first="Gustavo" last="Scola">Gustavo Scola</name><name sortKey="Scola, Gustavo" sort="Scola, Gustavo" uniqKey="Scola G" first="Gustavo" last="Scola">Gustavo Scola</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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